Production and evaluation of recombinant Burkholderia pseudomallei GroEL and OmpA proteins for serodiagnosis of melioidosis

Kanyanan Kritsiriwuthinan,Sumet Wajanarogana,Kantima Choosang, Jetsada Homsian, Sukritta Rerkthanom

Acta Tropica（2018）

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摘要

•The recombinant B. pseudomallei GroEL and OmpA proteins were produced.•The purified recombinant proteins were evaluated as antigens for melioidosis diagnosis by ELISA.•The rGroEL ELISA achieved a good sensitivity and specificity for melioidosis diagnosis.•The recombinant B. pseudomallei GroEL protein will be a potential antigen for further serodiagnosis development.

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关键词

Melioidosis,Burkholderia pseudomallei,Serodiagnosis,Recombinant protein

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