Draft genome sequences of three multidrug-resistant Cutibacterium (formerly Propionibacterium) acnes strains isolated from acne patients, China.

Cutibacterium acnes (formerly Propionibacterium acnes), an anaerobic Gram-positive bacterium, is a skin commensal and considered to be associated with acne. Here we report draft genome sequences of three multidrug-resistant C. acnes strains (CA17, CA39, and CA51), isolated from skin lesions of acne patients from China.The whole genome of the three multidrug-resistant C. acnes strains were sequenced using an Illumina HiSeq 2500 platform. De novo assembly and annotation were performed with SPAdes-3.5.0 and NCBI Prokaryotic Genome Annotation Pipeline (PGAP), respectively.The genomes of the three strains are as follows: 2 488 255bp containing 2494 genes and 2266 coding sequences (CDSs) for CA17; 2 484 088bp containing 2515 genes and 2376 CDSs for CA39; 2 483 437bp containing 2515 genes and 2372 CDSs for CA51. Each strain has 45 tRNAs and 3 rRNAs.The genome sequences of the three multidrug-resistant C. acnes strains may provide foundations for further research in resistance mechanism of antibiotic-resistant C. acnes strains and its role in disease pathogenesis.