Detection Of Spotted Fever Group Rickettsia Dna By Deep Sequencing
EMERGING INFECTIOUS DISEASES（2017）
Abstract
After conventional molecular and serologic testing failed to diagnose the cause of illness, deep sequencing identified spotted fever group Rickettsia DNA in a patient's blood sample. Sequences belonged to R. honei, the causative agent of Flinders Island spotted fever. Next-generation sequencing is proving to be a useful tool for clinical diagnostics.
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Key words
Australia,DNA,Rickettsia,bacteria,deep sequencing,etiology,fever,genome,rash,sequence analysis,spotted fever group
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