A brief review on the immunological scenario and recent developmental status of vaccines against enteric fever.

•Preventive measures of typhoidal salmonellae infection in the population, along with epidemiological status of the infection.•Importance of seroprevalence and identification of chronic carriage.•Existing animal models and different routes of vaccine administration and their effects.•New generation non-living vaccines in the form of bacterial Outer Membrane Vesicles (OMVs).•Loopholes of present typhoidal salmonellae vaccine research and future perspectives.