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A gammaherpesvirus provides protection against allergic asthma by inducing the replacement of resident alveolar macrophages with regulatory monocytes

Bénédicte Machiels,Mickael Dourcy,Xue Xiao,Justine Javaux,Claire Mesnil,Catherine Sabatel,Daniel Desmecht,François Lallemand,Philippe Martinive,Hamida Hammad,Martin Guilliams,Benjamin Dewals,Alain Vanderplasschen,Bart N Lambrecht,Fabrice Bureau,Laurent Gillet

NATURE IMMUNOLOGY（2017）

Cited 62|Views25
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Abstract
Gillet and colleagues find that infection with a gammaherpesvirus confers strong and lasting protection against airway allergy through the replacement of lung-resident alveolar macrophages with recruited regulatory monocytes of bone marrow origin.
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Key words
Alveolar macrophages,Asthma,Viral infection,Virology,Biomedicine,general,Immunology,Infectious Diseases
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