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Sympathetic neuron–associated macrophages contribute to obesity by importing and metabolizing norepinephrine

Roksana M Pirzgalska,Elsa Seixas,Jason S Seidman,Verena M Link,Noelia Martínez Sánchez,Inês Mahú,Raquel Mendes,Vitka Gres,Nadiya Kubasova,Imogen Morris,Bernardo A Arús,Chelsea M Larabee,Miguel Vasques,Francisco Tortosa,Ana L Sousa, Sathyavathy Anandan,Erin Tranfield,Maureen K Hahn,Matteo Iannacone,Nathanael J Spann,Christopher K Glass,Ana I Domingos

NATURE MEDICINE（2017）

Cited 321|Views31
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Abstract
Sympathetic neuron–associated macrophages act as a local sink for norepinephrine, leading to reduced thermogenesis and increased obesity.
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Key words
Immunology,Metabolic disorders,Neuroimmunology,Biomedicine,general,Cancer Research,Metabolic Diseases,Infectious Diseases,Molecular Medicine,Neurosciences
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