Pharmacoresistance with newer anti-epileptic drugs in mesial temporal lobe epilepsy with hippocampal sclerosis.

Epilepsy Research(2017)

Cited 23|Views1
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Abstract
•The majority (75.3%) of patients with MTLE-HS remain refractory to 2 or more appropriate AED trials.•Newer AEDs are not more likely to control seizures in MTLE-HS than older AEDs.•Duration of epilepsy significantly correlates with number of AED trials in seizure free but not pharmacoresistant patients.
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Key words
Anti-epileptic drugs,Epilepsy surgery,Hippocampal sclerosis,Natural history studies (prognosis),MRI
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