Lgr6 is a stem cell marker in mouse skin squamous cell carcinoma

NATURE GENETICS(2017)

引用 46|浏览76
暂无评分
摘要
Lineage-tracing experiments in the mouse show that Lgr6 , but not Lgr5 , functions as a cancer stem marker in skin squamous cell carcinomas (SCCs). The authors also show that Lgr6 -knockout mice are predisposed to SCC development, through a mechanism that includes compensatory upregulation of Lgr5 .
更多
查看译文
关键词
Squamous cell carcinoma
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要