Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection

Estefania Fernandez,Wanwisa Dejnirattisai,Bin Cao,Suzanne M Scheaffer,Piyada Supasa,Wiyada Wongwiwat,Prabagaran Esakky,Andrea Drury,Juthathip Mongkolsapaya,Kelle H Moley,Indira U Mysorekar,Gavin R Screaton,Michael S Diamond

NATURE IMMUNOLOGY（2017）

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摘要

Diamond, Screaton and colleagues show that certain cross-reactive neutralizing antibodies to dengue virus have therapeutic activity against Zika virus infection in immune-privileged sites in vivo .

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Virology

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