Ex vivo trypanocidal activity of 1-(2-hydroxybenzylidene)thiosemicarbazide against Trypanosoma equiperdum.

N Parra, M Jaume, K Boscán, A Hernández,A Mijares, M González,Y Alvarado,J Restrepo

Veterinary Parasitology（2017）

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摘要

•A thiosemicarbazone derivate showed a dose-dependent effect on T. equiperdum.•The compound exhibits an IC50 value lower than the drug commonly used.•A substitution of a hydroxyl group could increase the anti-trypanocidal activity.

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关键词

Thiosemicarbazone,Trypanosoma equiperdum,ex vivo effect

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