Downregulation of FOXP3 inhibits cell proliferation and enhances chemosensitivity to cisplatin in human lung adenocarcinoma.

Chun Li,Liwei Sun,Rui Jiang,Peng Wang,Haogang Xue,Yudong Zhan,Xiaodong Gai

Pathology - Research and Practice（2017）

Cited 10|Views2

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Abstract

•FOXP3 is associated with lymph node metastasis and TNM stage of lung adenocarcinoma (LAD) patients.•FOXP3 is correlated with Ki-67 and plays a positive role in cell growth of LAD.•FOXP3 could reduce chemosensitivity to cisplatin in LAD cells.

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Key words

FOXP3,Lung adenocarcinoma,Ki-67,Chemosensitivity,Cisplatin

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