High-throughput flow cytometry for drug discovery: principles, applications, and case studies.
Drug Discovery Today(2017)
Abstract
•HT flow cytometry is a versatile technology applicable to HTS, phenotypic or target-based screening, multiplex compound profiling etc.•Multiplexing is a key strength of HT flow cytometry allowing multiple endpoints to be measured simultaneously.•Case studies covering HTS, phenotypic, SAR screening and compound profiling are presented.
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