A semantic interoperability approach to support integration of gene expression and clinical data in breast cancer
Computers in Biology and Medicine(2017)
Abstract
•Standard-based semantic interoperability solution integrating clinical and genomic data.•Use of biomedical standards (HL7, SNOMED, HGNC) and IHE recommendations.•It has been used for testing in diagnostic classifier tool.•Clinical variables and gene expression data are retrieved through SPARQL for feeding biomedical tools.
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Key words
Clinical research informatics,Semantic interoperability,Data integration,Diagnostic classifier,Gene expressions,Biomedical terminologies
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