Oscillatory stimuli differentiate adapting circuit topologies
NATURE METHODS(2017)
Abstract
Negative feedback and incoherent feed-forward loops are the only circuit motifs that can adapt in response to stimuli. Rahi et al . describe signatures that allow discriminating between these two motifs and demonstrate the approach in yeast cell cycle timing and C. elegans olfaction.
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Key words
Biochemical reaction networks,Cell growth,Computational biophysics,Molecular neuroscience,Network topology,Life Sciences,general,Biological Techniques,Biological Microscopy,Biomedical Engineering/Biotechnology,Bioinformatics,Proteomics
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