Mathematical modeling of spatiotemporal protein localization patterns in C. crescentus bacteria: a mechanism for asymmetric FtsZ ring positioning.
Journal of Theoretical Biology（2017）
Abstract
•Preferential ParA dimerization at the new pole matrix guides chromosome segregation.•Asymmetric MipZ dimer gradients arise when MipZ and ParA compete for access to ParB.•ParA oscillations arise when cytoplasmic PopZ oligomers engage dynamically with ParA.•Variations in ParA/B localizations affect MipZ dimer gradients and Z-ring placement.
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Key words
Par protein gradients,Bipolar MipZ,Z-ring placement,C. crescentus
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