Double Blind Randomized Phase III Study of Maintenance Pazopanib® (Pz) Versus Placebo (P) in Non Small Cell Lung Cancer (Nsclc) Patients (Pts) Non Progressive After First Line Chemotherapy [Ct] (Eortc Lung Cancer Group, 08092): Mapping

M.E.R. O'Brien,R. Gaafar,B. Hasan,J. Menis,T. Cufer,S. Popat,P. Woll,V. Surmont, V. Georgoulias, A. Montes,F. Blackhall, I. Hennig, G. Schmid-Bindert,P. Baas

Annals of Oncology(2014)

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摘要
Aim: Switch maintenance is an effective strategy in advanced NSCLC treatment. Pz is an orally active, multi-targeted tyrosine kinase inhibitor (TKI), potentially effective in lung cancer. EORTC 08092 evaluated Pz given as maintenance following standard first line platinum-based chemotherapy (CT) in pts with advanced NSCLC.
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