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C1q/tumor necrosis factor-related protein-3 enhances the contractility of cardiomyocyte by increasing calcium sensitivity.

Cheng-Lin Zhang,Zheng-Ju Chen,Han Feng,Qian Zhao,Yang-Po Cao,Li Li,Jin-Yu Wang,Yan Zhang,Li-Ling Wu

Cell Calcium（2017）

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Abstract
•CTRP3 increases the contractility of cardiomyocytes.•CTRP3 does not alter the Ca2+ transient and ICa of cardiomyocytes.•CTRP3 increases the Ca2+ sensitivity of cardiomyocytes.•CTRP3 induced cTnI dephosphorylation might mediated by PP2A.
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Key words
CTRP3,cTnI,cTnC,ICa,MI,PP2A
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