CpG oligonucleotides increase HBV-specific cytokine responses in whole blood and enhance cytokine release assay sensitivity.

Werner Dammermann, Julia Dornbrack,Katharina Bröker,Frank Bentzien,Stefan Lüth

Journal of Virological Methods（2017）

引用 4|浏览8

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摘要

•We describe an improved HBV-specific cytokine release assay.•CpG oligonucleotides enhanced HBsAg-mediated IL2 & IFNγ responses in whole blood.•Additional CpG stimulation increased diagnostic sensitivity.

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关键词

HBV,TLR,HBsAg,HBcAg

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