Association of descending thoracic aortic plaque with brain atrophy and white matter hyperintensities: The Framingham Heart Study.

Hugo J Aparicio,Rodica E Petrea,Joseph M Massaro,Warren J Manning,Noriko Oyama-Manabe,Alexa S Beiser,Carlos S Kase,Ralph B D'Agostino,Philip A Wolf,Ramachandran S Vasan,Charles DeCarli,Christopher J O'Donnell,Sudha Seshadri

Atherosclerosis（2017）

引用 12|浏览11

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摘要

•Atheromatous plaque in the descending aorta was associated with lower brain volume.•Brain volume loss was equivalent to 8.8 years of aging in women, 4.5 years overall.•White matter hyperintensity volume was increased in men with thoracic aortic plaque.•Plaque in the descending aorta was not associated with subsequent stroke/TIA.

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关键词

Aorta,Atherosclerosis,Brain,Cerebrovascular disorders,Magnetic resonance imaging,Neuroimaging,White matter

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