Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells

NATURE（2017）

引用 299|浏览57

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摘要

The inflammasome receptor Nlrp9b defends against enteric viruses by interacting with double-stranded viral RNA-bound helicase Dhx9, triggering gasdermin-D-dependent pyroptotic cell death of infected cells and secretion of Il-18.

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关键词

NOD-like receptors,Viral infection,Science,Humanities and Social Sciences,multidisciplinary

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