Search
ChatPaper
AI Writing
analysis
Analysis
编组
Open Data
more
More
RankingsMust ReadingJournal&ConferenceAI TRAI HistoryMaster Reading TreeXiaomai's Star TalentsTrajectoryTalentNDI TrackerOpenAI sign Language
VIPCreated with Sketch.

β-Lactone formation during product release from a nonribosomal peptide synthetase

Jason E Schaffer, Margaret R Reck,Neha K Prasad,Timothy A Wencewicz

Nature Chemical Biology（2017）

Cited 71|Views9
No score
Abstract
In vitro reconstitution of five enzymes elucidates the biosynthetic pathway of obafluorin (Obi) and reveals that ObiF uses an unusual thioesterase domain to cyclize the product to a strained β-lactone during release from the NRPS assembly line.
More
Translated text
Key words
Biosynthesis,Natural products,Enzymes,Enzyme mechanisms
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined