Drug response consistency in CCLE and CGP

Mehdi Bouhaddou, Matthew S. DiStefano,Eric A. Riesel, Emilce Carrasco, Hadassa Y. Holzapfel,DeAnalisa C. Jones,Gregory R. Smith,Alan D. Stern,Sulaiman S. Somani,T. Victoria Thompson,Marc R. Birtwistle

NATURE（2016）

引用 73|浏览4

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摘要

arising from B. Haibe-Kains et al. Nature 504, 389–393 (2013); doi:10.1038/nature12831 The Cancer Cell Line Encyclopedia1 (CCLE) and Cancer Genome Project2 (CGP) are two independent large-scale efforts to characterize genomes, mRNA expression, and anti-cancer drug dose–responses across cell lines, providing a public resource relating cellular biochemical context to drug sensitivity.… Download references

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Targeted therapies,Systems biology,Pharmacology,Cancer

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