Mitochondrial Proteomic Alterations Caused by Long-term Low-dose Copper Exposure in Mouse Cortex.

Xuemei Lin,Gang Wei,Zhijun Huang,Zhongsen Qu,Xinfeng Huang,Hua Xu,Jianjun Liu,Zhixiong Zhuang,Xifei Yang

Toxicology Letters（2016）

引用 16|浏览14

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摘要

•Copper caused abnormal expression of mitochondrial proteins in brains.•Functional categories of the proteins affected by copper were revealed.•GRP75/GRP78 may be the key players in copper neurotoxicity.

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关键词

Proteomics,Mitochondria,Copper,Neurotoxicity

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