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Bimodal modulation of store-operated Ca2+ channels by clozapine in astrocytes

Yuzuki Kanda,Miho Okada,Rina Ikarashi,Eri Morioka,Takashi Kondo,Masayuki Ikeda

Neuroscience Letters（2016）

Cited 4|Views7
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Abstract
•Clozapine gates store-operated Ca2+ channels in astrocytes under normal conditions.•Clozapine inhibits store-operated Ca2+ entry in activated channels.•These effects are independent of pharmacological actions shared with olanzapine.
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ANOVA,2-APB,BSS,CCD,Clz,EGTA,GAPDH,Olz,5-HT,RT-PCR
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