Impaired Pulmonary Endothelial Barrier Function In Sickle Cell Mice

Nagavedi S. Umapathy,Joyce Gonzales,Levi H. Makala,Hongyan Xu,Paul Biddinger,Betty S. Pace

HAEMATOLOGICA（2017）

Cited 5|Views26

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Abstract

Acute and chronic pulmonary complications leading to significant morbidity and mortality occur in persons with sickle cell disease (SCD). One of the leading causes of death is acute chest syndrome (ACS),[1][1] diagnosed by a new infiltrate on chest x-ray often triggered by infection.[2][2] The

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