Search
ChatPaper
AI Writing
analysis
Analysis
编组
Open Data
more
More
RankingsMust ReadingJournal&ConferenceAI TRAI HistoryMaster Reading TreeXiaomai's Star TalentsTrajectoryTalentNDI TrackerOpenAI sign Language
VIPCreated with Sketch.

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation

Kuan-Chuan Pao,Mathew Stanley, Cong Han,Yu-Chiang Lai,Paul Murphy,Kristin Balk,Nicola T Wood,Olga Corti,Jean-Christophe Corvol,Miratul M K Muqit,Satpal Virdee

Nature Chemical Biology（2016）

Cited 73|Views7
No score
Abstract
Probes of E3 ligase transthiolation activity reveal the hierarchy of phosphorylation events leading to cellular parkin activation and show that disease-linked parkin mutants have impaired transthiolation activity.
More
Translated text
Key words
Cell signalling,Chemical tools,Neurodegenerative diseases,Post-translational modifications,Chemistry/Food Science,general,Biochemical Engineering,Biochemistry,Cell Biology,Bioorganic Chemistry
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined