Pre-fusion structure of a human coronavirus spike protein

Robert N. Kirchdoerfer,Christopher A. Cottrell,Nianshuang Wang,Jesper Pallesen,Hadi M. Yassine,Hannah L. Turner,Kizzmekia S. Corbett,Barney S. Graham,Jason S. McLellan,Andrew B. Ward

Nature（2016）

引用 809|浏览14

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摘要

4.0 Å resolution cryo-electron microscopy structure of the pre-fusion form of the trimeric spike from the human coronavirus HKU1 provides insight into how the spike protein mediates host-cell attachment and membrane fusion.

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关键词

Cryoelectron microscopy,SARS virus,Science,Humanities and Social Sciences,multidisciplinary

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