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Godzilla-dependent transcytosis promotes Wingless signalling in Drosophila wing imaginal discs

Yasuo Yamazaki,Lucy Palmer,Cyrille Alexandre,Satoshi Kakugawa,Karen Beckett,Isabelle Gaugue,Ruth H. Palmer,Jean-Paul Vincent

NATURE CELL BIOLOGY（2016）

Cited 69|Views3
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Abstract
Vincent and colleagues show in Drosophila wing imaginal discs that the signalling molecule Wingless is synthesized and secreted at the apical surface, and is re-internalized to be transcytosed basally, where its signalling occurs.
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Key words
Drosophila,Endocytosis,Exocytosis,Ubiquitin ligases
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