Changes in T Lymphocyte Subsets in Different Tumors Before and After Radiotherapy: A Meta-Analysis.
International journal of radiation oncology, biology, physics(2021)
Abstract
Numbers of CD3+ and CD4+ T lymphocytes decreased after radiotherapy, whereas CD8+ T lymphocytes showed no significant change. Within 1 month of radiotherapy, the tumor microenvironment showed an immunosuppressive state. The degree of immune response induced by radiotherapy differed between tumor types.
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