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Overcoming EGFR(T790M) and EGFR(C797S) Resistance with Mutant-Selective Allosteric Inhibitors.

Yong Jia,Cai-Hong Yun,Eunyoung Park,Dalia Ercan,Mari Manuia,Jose Juarez,Chunxiao Xu,Kevin Rhee,Ting Chen,Haikuo Zhang,Sangeetha Palakurthi,Jaebong Jang,Gerald Lelais,Michael DiDonato,Badry Bursulaya,Pierre-Yves Michellys,Robert Epple,Thomas H. Marsilje,Matthew McNeill,Wenshuo Lu,Jennifer Harris,Steven Bender,Kwok-Kin Wong,Pasi A. Jänne,Michael J. Eck

Nature（2016）

Cited 789|Views38
Key words
Cancer,Drug discovery,Kinases,Non-small-cell lung cancer,X-ray crystallography,Science,Humanities and Social Sciences,multidisciplinary
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