Control of the innate immune response by the mevalonate pathway

Murali K Akula, Man Shi,Zhaozhao Jiang, Celia E Foster,David Miao, Annie S Li, Xiaoman Zhang, Ruth M Gavin,Sorcha D Forde,Gail Germain,Susan Carpenter,Charles V Rosadini,Kira Gritsman,Jae Jin Chae,Randolph Hampton,Neal Silverman,Ellen M Gravallese,Jonathan C Kagan,Katherine A Fitzgerald,Daniel L Kastner,Douglas T Golenbock,Martin O Bergo,Donghai Wang

NATURE IMMUNOLOGY（2016）

引用 149|浏览0

暂无评分

摘要

Deficiency in mevalonate kinase causes autoinflammatory disease. Wang and colleagues define the detailed mechanistic basis that leads to this disease phenotype in mice and humans.

查看译文

关键词

Inflammasome,Toll-like receptors,Autoinflammatory syndrome

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要