Stimulating the RIG-I pathway to kill cells in the latent HIV reservoir following viral reactivation
NATURE MEDICINE（2016）
Abstract
Li et al . show that the retinoic acid derivative acitretin activates HIV-1 transcription in latently infected T cells and induces RIG-I signaling, which leads to cell death and suggests an approach to reduce the HIV reservoir.
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Key words
HIV infections,Translational research
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