The mouse cortico-striatal projectome

Houri Hintiryan,Nicholas N Foster,Ian Bowman,Maxwell Bay,Monica Y Song,Lin Gou,Seita Yamashita,Michael S Bienkowski,Brian Zingg,Muye Zhu,X William Yang,Jean C Shih,Arthur W Toga,Hong-Wei Dong

NATURE NEUROSCIENCE（2016）

引用 357|浏览8

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摘要

Hintiryan, Foster et al . present an online mouse cortico-striatal projectome describing projections from the entire cortex to dorsal striatum. Computational neuroanatomic analysis of these projections identified 29 distinct striatal domains. This connectomics approach was applied to characterize circuit-specific cortico-striatal connectopathies in a mouse model of Huntington disease and in monoamine oxidase (MAO) A/B knockout mice.

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关键词

Neural circuits,Network models,Striatum

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