Precursors of tRNAs are stabilized by methylguanosine cap structures

NATURE CHEMICAL BIOLOGY（2016）

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摘要

MS analysis of yeast transfer RNA precursors (pre-tRNAs) isolated at different stages of tRNA processing and maturation reveals the presence of 5′-terminal methylguanosine cap structures that protect pre-tRNA from 5′-exonucleolytic degradation.

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关键词

RNA modification,RNA,Post-translational modifications,Enzymes

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