Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction
NATURE BIOTECHNOLOGY(2016)
摘要
genome-wide, strand-specific sequencing method to detect 5-hydroxymethylcytosine marks in single cells is developed.
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关键词
Genomic analysis,Epigenomics,Stochastic modelling,Molecular fluctuations
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