Free backbone carbonyls mediate rhodopsin activation

Naoki Kimata,Andreyah Pope,Omar B Sanchez-Reyes,Markus Eilers,Chikwado A Opefi,Martine Ziliox,Philip J Reeves,Steven O Smith

NATURE STRUCTURAL & MOLECULAR BIOLOGY（2016）

引用 15|浏览21

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摘要

Solid-state NMR analyses reveal that the free backbone carbonyl groups associated with proline residues in the transmembrane helices play a key role in mediating rhodopsin activation.

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关键词

Solid-state NMR,Enzyme mechanisms,Membrane biophysics

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