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Complementarity Determining Region-Independent Recognition Of A Superantigen By B-Cell Antigen Receptors Of Mantle Cell Lymphoma

Michael Fichtner,Elmar Spies,Henning Seismann,Kristoffer Riecken,Niklas Engels, Barbara Gosch,Judith Dierlamm,Helwe Gerull,Peter Nollau,Wolfram Klapper,Martin Dreyling,Mascha Binder,Martin Trepel

HAEMATOLOGICA（2016）

Cited 10|Views43
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Abstract
The past two decades of lymphoma research have uncovered the essential role of the B-cell antigen receptor (BCR) pathway in lymphoma biology. This resulted in the development of targeted inhibitors for the treatment of several B-cell malignancies, especially chronic lymphocytic leukemia (CLL),
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Key words
superantigen,mantle cell lymphoma,B-cell receptor,protein A,SpA
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