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Tcf1 and Lef1 pack their own HDAC

Charles P Ng,Dan R Littman

Nature immunology（2016）

Cited 7|Views3
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Abstract
The transcription factors Tcf1 and Lef1 have intrinsic histone-deacetylase activity that is required for the repression of CD4 + T cell–lineage genes in CD8 + T cells.
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Key words
CD4-positive T cells,CD8-positive T cells,Chromatin remodelling,Biomedicine,general,Immunology,Infectious Diseases
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