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Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer

Andrew McPherson,Andrew Roth,Emma Laks,Tehmina Masud,Ali Bashashati,Allen W Zhang,Gavin Ha,Justina Biele,Damian Yap,Adrian Wan,Leah M Prentice,Jaswinder Khattra,Maia A Smith,Cydney B Nielsen,Sarah C Mullaly,Steve Kalloger,Anthony Karnezis,Karey Shumansky,Celia Siu,Jamie Rosner, Hector Li Chan,Julie Ho,Nataliya Melnyk,Janine Senz,Winnie Yang, Richard Moore,Andrew J Mungall,Marco A Marra,Alexandre Bouchard-Côté,C Blake Gilks,David G Huntsman,Jessica N McAlpine,Samuel Aparicio,Sohrab P Shah

NATURE GENETICS（2016）

Cited 267|Views106
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Abstract
Sohrab Shah, Samuel Aparicio and colleagues analyze whole genomes and single cells from ovarian cancers in the peritoneal cavity to establish patterns of disease spread. They determine the clonal relationships between multiple tumor sites and characterize the migratory potential of genomically diverse clones.
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Key words
Genome informatics,Ovarian cancer,Ovarian cancer
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