Antibody Detection Tests for Early Diagnosis in Tuberculous Meningitis.
International Journal of Infectious Diseases(2016)
Abstract
•A systematic review was performed to assess the diagnostic accuracy of antibody detection tests for tuberculous meningitis (TBM).•For the diagnosis of patients thought to have TBM based on antibodies in the cerebrospinal fluid (CSF), the detection of anti-M37Ra, anti-antigen 5, or anti-M37Rv provides the greatest sensitivity and specificity.•Antibody detection tests could be translated into rapid point-of-care tests; research to improve their performance is urgently needed.
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Key words
Diagnosis,Antibody detection tests,Tuberculous meningitis,Cerebrospinal fluid
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