Postmortem detection of antibiotic-specific immunoglobulin E in the case of anaphylactic death.

Motonori Takahashi, Takeshi Kondo,Mai Morichika,Azumi Kuse,Kanako Nakagawa,Yasuhiro Ueno

Forensic Science International（2016）

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摘要

•Antigen-specific IgE is a key molecule in an allergic anaphylactic reaction.•IgE for a low molecular weight chemical is detected by a pull-down assay.•Detection of antigen-specific IgE supports a postmortem diagnosis of anaphylaxis.

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关键词

Pull-down assay,Ceftriaxone,Amine coupling,Anaphylaxis

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