IL-17A promotes microglial activation and neuroinflammation in mouse models of intracerebral haemorrhage.

•IL-17A Ab prevented ICH-induced cytokine expression and downstream signaling molecules.•IL-17A Ab attenuated microglial activation.•IL-17A Ab significantly reduced brain water content and improved neurological function of ICH mice.•IL-17A Ab might also provide a promising therapeutic strategy in ICH.