A novel mechanism of NPM1 cytoplasmic localization in acute myeloid leukemia: the recurrent gene fusion NPM1-HAUS1.

Paulo Vidal Campregher,Welbert de Oliveira Pereira,Bianca Lisboa,Renato Puga,Elvira Rodrigues Pereira Velloso Deolinda,Ricardo Helman,Luciana Cavalheiro Marti,João Carlos Campos Guerra,Kalliopi N Manola,Roberta Cardoso Petroni,Alanna Mara Pinheiro Sobreira Bezerra,Fernando Ferreira Costa,Nelson Hamerschlak,Fábio Pires de Souza Santos

HAEMATOLOGICA（2016）

引用 11|浏览30

暂无评分

摘要

NPM1 heterozygous mutations are present in roughly a third of patients with acute myeloid leukemia (AML), making it one of the most frequent genomic alterations in these patients.[1][1] The mutations are characterized by frameshift insertions in the region encoding the C-terminus of the protein,

查看译文

关键词

acute myeloid leukemia,nucleophosmin,gene fusion

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要