Deoxynivalenol inhibits proliferation and induces apoptosis in human umbilical vein endothelial cells.
Environmental Toxicology and Pharmacology（2016）
Abstract
•DON significantly inhibited the viability of human umbilical vein endothelial cells (HUVECs).•DON inhibited the proliferation of HUVECs through G2/M phase arrest in cell cycle progression.•DON could induce oxidative stress, and apoptosis in HUVECs.
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Key words
Deoxynivalenol,HUVECs,Mitochondrial membrane potential,Cell cycle,Apoptosis
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