The role of inflammatory parameters in the diagnosis and management of patients with community-acquired pneumonia

The aim of this study was to determine whether there is a significant difference between the values of C-reactive protein (CRP) and white blood cells (WBC), in patients with serological proved atypical pneumonia and in serological negative atypical pneumonia. Materials and methods: A total of 403 adult hospitalized patients with clinical and radiographic findings of pneumonia. Diagnosis of acute atypical pneumonia was established by serological confirmation of IgM and IgG antibody against Mycoplasma pn., Coxiella burneti, Chlamydia pn. and Legionella pn. There were compared the values of the age, sedimentation, WBC, lymphocytes, neutrophils, CRP and aminotranspherases in patients with pneumonia with atypical infection (n=145) and in serological negative for atypical pathogen (n=248). Results: The mean age of patients was 49,86 years, 209 (51,86%) were male and 194 (48,14%) female. Atypical acute infection there was in 145 (35,98%), in 10 (2,48%) mixed etiology and 248 (61,54%) were negative for atypical pathogen. The main value of the age in patients with positive result for atypical pathogen was statistical significance lower (t=-4,39, p