Serum 25(OH)vitamin D level and Its correlation with bone mineral density in girls with Adolescent Idiopathic Scoliosis (AIS)

Objectives AIS is associated with both low bone mass and elevated serum bone alkaline phosphatase. It was also reported the prevalence of AIS was positively correlated with the latitude of the geographical region. These specific features were compatible with the presence of either Vit-D insufficiency or abnormal physiology with Vit-D. It is important to evaluate these potentially treatable conditions regarding their roles in the etiopathogenesis of AIS. The objectives of this case-control study were to evaluate Vit-D status and its correlation with areal bone mineral density (aBMD) in AIS subjects and normal controls.