The Evaluation And Comparison Of The Alpha And Beta Amanitin Toxicity On Mcf-7 Cell Line

To evaluate the efficacy of Rhodiola rosea (R. rose) extract in terms of preventing tissue injury induced by testicular torsion and subsequent ischemia/reperfusion (I/R).Twenty-one Wistar albino male rats were divided into 3 groups: group 1 = control group, group 2 = I/R group, and group 3 = I/R + extract group. After 2 hours of ischemia and 4 hours of reperfusion, testes were removed and evaluated histologically by hematoxylin and eosin staining. Apoptosis in spermatogonial cells of seminiferous tubules was determined by transferase biotin-2′-deoxyuridine, 5′-triphosphate nick end labeling (TUNEL). To assess oxidative damage, serum malondialdehyde (MDA) and glutathione (GSH) levels were measured.Median MDA and GSH levels were, respectively, 12 ± 3 pmol/mL and 24.8 ± 3.8 μM in group 1, 38 ± 11 pmol/mL and 10.3 ± 1.7 μM in group 2, and 19 ± 5 pmol/mL and 17.6 ± 1.3 μM in group 3 (P