Acute Cerebellar Ataxia Associated with Mycoplasma pneumonia Infection

Nervous system is the most frequently affected system by Mycoplasma pneumoniae infections other than respiratory system two patients who were admitted with acute cerebellar ataxia and whose serological tests were positive for Mycoplasma pneumoniae are reported. A 6-year-old girl with acute ataxia and cerebellar symptoms and the other, seven-year-old girl suffering from nausea, vomiting and fatigue for 4 days were admitted to our hospital. Ataxia and cerebellar symptoms were found during their neurologic examination. Results of routine hematologic, and biochemical tests, cranial Magnetic Resonance Imaging (MRI), Cerebrospinal fluid (CSF), and serum microbiological analyses were within normal limits, but M. pneumonia IgM and IgG positivities were detected. Clarithromycine treatment was initiated, and cerebellar symptoms were resolved on the second day of therapy in the first patient and third day in the second patient. M.pneumonia can be responsible for acute cerebellar ataxia of otherwise unexplained origin. Besides, neurologic symptoms may improve with antibiotherapy