Multi-scale model for hepatitis C viral load kinetics under treatment with direct acting antivirals
Virus Research(2016)
摘要
•We developed a multi-scale model of hepatitis C virus infection.•Patient-level processes and molecular details of viral replication are considered.•Our model reproduces clinical time-course data of viral load under antiviral treatment.•We predict treatment efficacy of daclatasvir can be improved by combination therapy.
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HCV
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