Dissection of two modes of IE1 sub-nuclear localization in baculovirus-infected cells
Virus Research(2015)
Abstract
•We screened a chemical library with a recombinant baculovirus.•An inhibitor of baculovirus-IE1 focus formation, dBIQdO, was identified.•dBIQdO reduces viral titers following infection at a low MOI.•dBIQdO revealed that IE1 foci are not essential for virogenic-stroma formation.
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Key words
Baculovirus,NPV,Virogenic stroma,IE1,P143,Subnuclear structure
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